Another television series set in a hospital, but this one is a comedy and not a heart-wrenching drama. The story centers on intern John "J.D." Dorian (Zach Braff – Garden State, The Last Kiss) and the mishaps and other hilarities he encounters while learning to become a doctor. There are some serious moments in the series, but comedy is its bread and butter. The comedy is not your usual run-of-the-mill sitcom stuff, either. It is quirky, bizarre and definitely original. There are plenty of big guest stars in this season including Heather Graham (Boogie Nights, Bowfinger), Julianna Margulies (from television's ER), Molly Shannon (from television's Saturday Night Live), Clay Aikens (from television's American Idol), Colin Farrell (Phonebooth, Miami Vice), and Matthew Perry (from television's Friends).
Episode 1: My Old Friend's New Friend: The latest addition to the team is Dr. Molly Clock and she definitely is one of a kind. It is J.D.'s last week as a resident.
Episode 2: My Office: Dr. Clock tries to get J.D. and Elliot (Sarah Chalke – Ernest Goes to School) back together. J.D. and Elliot are both competing for the Chief Resident position.
Episode 3: My New Game: Turk (Donald Faison – Clueless, Uptown Girls) begins to doubt his talents as a physician. Dr. Cox (John C. McGinley – Any Given Sunday, Seven) and Clock have a disagreement about patient treatment.
Episode 4: My First Kill: Dr. Cox scares J.D. when he tells him that eventually all doctors kill a patient. J.D. thinks that it might happen soon.
Episode 5: Superb: J.D. does not know what to do when Dr. Cox yells at him in front of the interns. Carla (Judy Reyes – Bringing Out the Dead) and Turk adjust to married life.
Episode 6: My Cake: Dan (Tom Cavanagh – from television's Ed) returns and tells a shocked J.D. that their father has died. Turk finds out something disturbing about his health.
Episode 7: My Common Enemy: J.D. does not know what to do when he finds Dan and Elliot together. Dr. Cox and Dr. Kelso (Ken Jenkins – The Sum of All Fears, I Am Sam) unite to torment Dr. Clock.
Episode 8: My Last Chance: Dr. Clock announces that she will be leaving for a job in another city. J.D. tries to sleep with her before she leaves.
Episode 9: My Malpractice Decision, Part 1: J.D. is asked by a malpractice attourney to do perform a risky operation on her father. Turk tries to avoid a patient who is a hypochondriac.
Episode 10: My Female Trouble, Part 2: J.D. tries to break up with Neena. A case is brought against Turk.
Episode 11: My Unicorn: Elliot, who is sick of not being taken seriously, uses her sexuality to get what she wants.
Episode 12: My Best Moment: The staff thinks about their best moments in the health care profession. Elliot has to deal with her fear of children.
Episode 13: My Ocardial Infarction: Elliot begins to demonstrate that she is the better doctor than J.D. Turk begins to take his illness seriously.
Episode 14: My Lucky Charm: J.D. and Turk learn a thing or two about living life from a patient.
Episode 15: My Hypocritical Oath: Elliot challenges Dr. Kelso over the treatment of one of her patients. J.D. is attracted to a girl who has a boyfriend he knows something about.
Episode 16: My Quarantine: Turk finds out that Carla dated Dr. Cox. J.D. tries to impress a girl.
Episode 17: My Life in Four Cameras: J.D. meets a television writer and begins to imagine life at the hospital as a sitcom.
Episode 18: My Roommates: J.D. is kicked out of the apartment and Turk and Carla try to keep the romance alive.
Episode 19: My Best Laid Plans: J.D. dumps Kylie (Chrystee Pharris – from television's Passions) when Dr. Clock returns. Carla is mad that Turk keeps phoning an ex-girlfriend.
Episode 20: My Boss' Free Haircut: Carla tries to get sympathy from Elliot. J.D. and Turk have fun.
Episode 21: My Lips Are Sealed: In an attempt to give Turk some alone time, Carla and J.D. go out and get drunk, but they end up kissing.
Episode 22: My Big Move: Turk finds out about the kiss and is not speaking to J.D. and Carla. Dr. Cox reluctantly has to turn to Elliot for help with a patient.
Episode 23: My Faith in Humanity: Turk is not very participatory at couples' therapy. Janitor (Neil Flynn – Anchorman: The Legend of Ron Burgundy, Mean Girls) accidentally lets some rats out and they are all over the building.
Episode 24: My Drive-By: Elliot worries about going too fast with Jake (Josh Randall – from television's Ed). Dr. Cox teaches Turk a lesson.
Episode 25: My Changing Ways: Residency is over and J.D. moves out on his own. Elliot gets an interview at another hospital due to Jake.
-Will You Ever Be My Mentor?: Explores J.D.'s never-ending quest for Dr. Cox's approval
-The Sweethearts of Sacred Heart: An inside look at the loves and flirtations of Sacred Heart's women
-Donald Keeps Talking: An extended sit-down interview with actor Donald Faison
-The Weapons Chest: Spend some time with the show's "second squad" of actors
-Who Is That Man?: Discover the secrets of the mysterious Janitor
-Commentary on two episodes
-Scrubbed Out: Deleted scenes
-Alternate lines: A Second Opinion
-Music video by G Tom Mac: "Half"